Anastrozole is a medication used primarily in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is an aromatase inhibitor, which works by blocking the enzyme aromatase, responsible for converting androgens into estrogens. By reducing estrogen levels, Anastrozole helps prevent the growth of estrogen-dependent breast cancer cells. It is often prescribed as adjuvant therapy following surgery or radiation, or in metastatic cases. Anastrozole is generally well-tolerated, but common side effects may include hot flashes, joint pain, fatigue, and bone thinning. Regular monitoring of bone density and other parameters may be necessary during long-term use.
