Alteplase Actilyse IV 50mg Injection is a medication used as a thrombolytic agent to treat acute ischemic stroke, myocardial infarction (heart attack), and pulmonary embolism (PE). Alteplase Actilyse IV 50mg Injection contains alteplase, a recombinant tissue plasminogen activator (rtPA), which helps dissolve blood clots by converting plasminogen into plasmin, leading to the breakdown of fibrin in the clot. The 50 mg vial is typically administered via intravenous infusion in a controlled hospital setting. The Alteplase Actilyse IV 50mg Injection is most effective when administered as early as possible after the onset of symptoms, usually within a specific time window (e.g., within 4.5 hours for stroke). Like other thrombolytic agents, alteplase carries a risk of serious bleeding, including intracranial hemorrhage, and must be carefully monitored during administration.